Compared to surface-to-surface contact with a full solid model, line-to-surface contact can provide similar results using significantly less solution time.

Multipoint constraints (MPCs) provide biologically accurate boundary conditions.

The choice of units is critical for avoiding numerical difficulties. For biological problems, millimeters-micron units are preferred.

To achieve faster solutions, coincident nodes and surfaces are preferred over bonded contact.

Stabilization mitigates convergence issues in unstable nonlinear problems.